Does cytotoxicity of metallointercalators correlate with cellular uptake or DNA affinity?
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چکیده
منابع مشابه
Does cytotoxicity of metallointercalators correlate with cellular uptake or DNA affinity?
The cytotoxicity of the metallointercalators, [Pt(5,6-dimethyl-1,10-phenanthroline)(trans-1R,2R-diaminocyclohexane)](2+) ([56MERR]) and [Pt(5,6-dimethyl-1,10-phenanthroline)(trans-1S,2S-diaminocyclohexane)](2+) ([56MESS]), towards A549 human lung cancer cells was examined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The IC(50) value obtained following expo...
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ژورنال
عنوان ژورنال: Dalton Transactions
سال: 2012
ISSN: 1477-9226,1477-9234
DOI: 10.1039/c2dt30217a